My research is driven by a central engineering question: how can quantitative principles of soft matter physics and fluid mechanics be used to build predictive models of human tissue function and disease? My goal is to turn quantitative interfacial mechanics into practical design rules for building predictive organs-on-chips and mechanistically grounded disease models.
I combine controlled microenvironments (geometry, flow, matrix mechanics, transport) with high-content assays to link physical variables to inflammation, immune dynamics, and therapeutic response. My current focus is on pulmonary and vascular microphysiological systems, including autologous iPSC-derived airway models relevant to Down syndrome (trisomy 21).
Google Scholar · LinkedIn · GitHub